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dc.contributor.advisorKang, Hong-Gu
dc.contributor.authorAfolabi, Oluwadamilare I. ( Orcid Icon 0000-0002-6985-8473 )
dc.date.accessioned2020-12-02T19:32:27Z
dc.date.available2020-12-02T19:32:27Z
dc.date.issued2020-12
dc.identifier.citationAfolabi, O. I. (2020). Identification of transcriptome dynamic patterns and their cognate cis-elements in defense genes in Arabidopsis (Unpublished thesis). Texas State University, San Marcos, Texas.
dc.identifier.urihttps://digital.library.txstate.edu/handle/10877/13031
dc.description.abstractSuccessful defense responses depend on the timely detection of pathogens and rapid transcriptional changes of defense genes. These transcriptional changes are mainly controlled by transcription factors binding to the regulatory regions of defense genes. To track these transcriptional changes and group these into a few related patterns, I analyzed the genome-wide expression profiles of Arabidopsis thaliana plants responding to Pseudomonas syringae infection at multiple times points. There are two distinct groups of defense genes rapidly upregulated or downregulated, reacting to Pseudomonas infection. I clustered these highly dynamical genes by their expression patterns into nine groups. I analyzed the gene ontology of each cluster and found that up-regulated clusters were mostly represented by traditional defense genes and down-regulated ones included a significant number of photosynthesis-related genes. Assessment of the promoter sequences also found that upregulated and downregulated clusters have distinct groups of cis-elements and their potential binding factors. In sum, my thesis research identified nine clusters with separable expression patterns and suggested a few candidate master regulators in transcriptional reprogramming associated with biotic stress in Arabidopsis.
dc.formatText
dc.format.extent64 pages
dc.format.medium1 file (.pdf)
dc.language.isoen
dc.subjectBiotic stress
dc.subjectArabidopsis thaliana
dc.subjectTranscriptome dynamics
dc.subjectCis-elements
dc.subject.lcshGenetic regulation
dc.titleIdentification of transcriptome dynamic patterns and their cognate cis-elements in defense genes in Arabidopsis
txstate.documenttypeThesis
dc.contributor.committeeMemberDharmasiri, Nihal
dc.contributor.committeeMemberDharmasiri, Sunethra
thesis.degree.departmentBiology
thesis.degree.disciplineBiology
thesis.degree.grantorTexas State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science
txstate.departmentBiology


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