A mathematical model describing cellular division with a proliferating phase duration depending on the maturity of cells

Date

2003-10-23

Authors

Adimy, Mostafa
Pujo-Menjouet, Laurent

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Publisher

Southwest Texas State University, Department of Mathematics

Abstract

In this paper, we investigate a linear population model of cells that are capable of simultaneous proliferation and maturation. We consider the case when the time required for a cell to divide depends on its maturity. This model is described by first order partial differential system with a retardation of the maturation variable and a time delay depending on this maturity. Both delays are due to cell replication.

Description

Keywords

Structured population, Cell cycle, Stem cells, First order partial differential equation with delays, Non constant delay

Citation

Adimy, M., & Pujo-Menjouet, L. (2003). A mathematical model describing cellular division with a proliferating phase duration depending on the maturity of cells. <i>Electronic Journal of Differential Equations, 2003</i>(107), pp. 1-14.

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Attribution 4.0 International

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