RSS 1.0Theses and Dissertations-Chemistry and Biochemistry
Browse by
Recent Submissions
-
Stability Studies of Rooperol and Analogues by In Vitro Metabolism With HPLC/MS Detection
(2019-04-29)African Potato, Hypoxis hemerocallidea, has a long history of use by the indigenous people of South Africa to treat cancer and a variety of other diseases. Extracts from the corm contain the norligan bisglycoside hypoxoside, ... -
Synthesis and Characterization of Novel Thiophene-Based Electroactive Polymers
(2019-04-25)Electroactive polymers show great promise in a variety of applications, from chemical sensors to energy storage. Their properties such as solubility and band gap can be tailored through the strategic addition of substituents ... -
Glucuronide Prodrug of a Naturally Derived Cytotoxic Product
(2019-04-26)<p>African Potato (Hypoxis hemerocallidea) is utilized as a medicinal plant in South Africa to treat disorders such as cancer, prostate hyperplasia, and cardiac disease. The corm of H. hemerocallidea contains high levels ... -
Elucidation of Critical Residues Within the Extracellular Loop of the Epithelial Sodium Channel
(2016-12-01)The epithelial sodium channel (ENaC) is a membrane protein complex located in the distal tubule of the nephron in the kidney which is responsible for the reabsorption of the final 3-5% of sodium from the urine back into ... -
Recombinant Expression and Purification of LARP6 Proteins from Arabidopsis thaliana
(2017-04-20)No abstract prepared. -
Aptamer-Based Biosensor for Platelet-Derived Growth Factor-bb using Fluorescence Resonance Energy Transfer
(2017-05-02)No abstract prepared. -
Polyaromatic Cores for Enhanced Conductivity in Inherently Conductive Polymers (ICPs)
(2017-07-21)The discovery of Inherently Conductive Polymers (ICPs), also known as “synthetic metals”, is an attracting class of materials as a promising alternative for metallic semiconductors and conductors, which combine the positive ... -
Biochemical Analysis of Evolutionary Divergent Vertebrate Larp6 Proteins
(2017-04-27)The La-related proteins (LARPs) contain a conserved bipartite RNA binding domain, called the La module, which consists of the La motif and an RNA recognition motif (RRM). Across the LARP subfamilies, the La module ... -
Characterizing the ligand specificity of the RNA binding protein LARP6
(2017-04-25)The La-related proteins are a superfamily of RNA-binding proteins characterized by a unique RNA binding domain that is comprised of two subdomains, the La motif (LAM) and the RNA recognition motif (RRM), which are connected ... -
-
Impact of Processing Parameters on Conductive Polymer Electroactivity
(2018-04-20)Soft-templating techniques have been applied to organic soluble polymer systems that produce a large variety of film morphologies. Film morphology is observed to greatly influence the system’s electrochemical current ... -
Determining the Role of ATP6V0E1 of the Vacuolar-ATPase in Regulating Neuroblastoma Cell Survival and Differentiation
(2018-04-24)Neuroblastoma is one of the leading causes of cancer-related childhood deaths. Neuroblastoma arises from the developing sympathetic nervous system where neural crest cells fail to complete the differentiation process. The ... -
Purification, Characterization, and Active Site Studies of 2-(2'-Hydroxyphenyl) Benzenesulfinate Desulfinase (DSZB) from Nocardia Asteroides Sp. Strain A3H1
(2009-12-05)Dibenzophene (DBT) and its complex heterocyclic derivatives comprise most of the sulfur that contaminates fossil fuels. The 2-(2´-hydroxyphenyl) benzenesulfinate desulfinase (DszB) enzyme metabolize sulfur from DBT compounds. ... -
-
Quantifying the ability of RF-amide neuropeptide analogs to promote amyloidosis of recombinant Human Prion Protein.
(2015-10-26)No abstract prepared. -
The Effects of Primary Sequence Perturbation on the Structure of Intrinsically Disordered Proteins
(2017-11-01)Intrinsically disordered proteins (IDPs) are a class of proteins that do not converge to a set of similar, energetically stable tertiary folds, but rapidly fluctuate between a wide variety of different accessible energy ... -
Click-Chemistry Based Molecularly Responsive Hydrogel as Biodegradable Scaffolds for 3-D Cell Culture: Design and Preparation of Building Blocks
(2014-07-28)According to the American Cancer Society, every year over one million Americans are diagnosed with one of the recognized forms of cancer. Cancer metastasis is associated with poor patient prognosis. In order to better ... -
