RSS 1.0Theses and Dissertations-Chemistry and Biochemistry
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Mechanisms of Human LARP6 Nuclear Export
(2019-05)The La Related Protein 6 (LARP6) regulates the expression of type I collagen synthesis by binding to the encoding mRNA. However, the molecular mechanism of ligand binding and cellular localization is not fully understood. ... -
Investigating the Novel Oncogenic Function of SAPCD2 in Pediatric Neuroblastoma
(2021-08)Pediatric neuroblastoma is the most common extra-cranial solid malignancy in infants and children. It is an aggressive neuroendocrine cancer that circumvents the normal differentiation process of sympathetic neuronal ... -
Novel Ambient Ionization Sampling Methodologies With Mass Spectrometry
(2020-05)Expanding on the current paradigm of ambient ionization, herein is reported the use of a metal surface for metal spray ionization and the use of online derivatization to separate isomass compounds. A metal surface has ...
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Using Heat Effects on Coil Hydrodynamic Size to Reveal the Nature and Energetics of Denatured State Conformational Bias
(2019-12)Conformational equilibria in the protein denatured state have key roles regulating folding, stability, and function. The extent of conformational bias in the denatured state under folding conditions, however, has thus far ... -
Purification and partial characterization of pokeweed antiviral protein immunoreactive species
(2001-05)No abstract prepared. -
Investigation of the mechanism of nucleophilic attack on the [trans-BH] anion
(2006-08)The substitution chemistry of the [trans-B20H18]2- anion was first investigated by Hawthorne and coworkers. The product formed from the reaction of the [trans-B20H18]2- anion with the hydroxide ion is an ...
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A survey of dimeric mu-bridged compounds and determination of unit cell dimensions of several Pt-complexes
(1971-05)The objective of the problem was to survey recent literature for all mu-bridged compounds and to determine the unit cell dimensions of several platinum complexes.
The literature survey was done using ...
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Role of telomerase in regulation of chromosome stability in cells lacking the Ku70/Ku80 heterodimer
(2008-08)No abstract prepared. -
Purification and characterization of 2-(2'-hydroxyphenyl) benzenesulfinate desulfinase from Nocardia asteroides strain sp A3H1
(2007-12)No abstract prepared. -
Defining the active site of 2-(2'-hydroxyphenyl) benzenesulfinate desulfinase
(2003-05)Diminishing resources of light crude oils containing low sulfur fractions have compelled petroleum refineries to process sour crude oils. Current sulfur removal processes include the use of hydrodesulfurization. ...
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Prevention of G-quadruplex folding by ligand-mediated stabilization of the G-triplex intermediate
(2018-12)G-quadruplex DNA is an extensively studied non-canonical DNA structure formed in guanine rich areas of the human genome. It is proposed that G-quadruplex structures play a role in telomere assembly, replication, and ... -
Low band gap donor-acceptor strategies for stable n-doping polymers
(2011-08)A promising approach for synthesizing stable n-doping polymers is to alternate electron donating and electron accepting moieties along a conjugated polymer backbone. The donors and acceptors used can be chosen to tailor ... -
Anti-biofouling polymetric windows: Additive effects on mechanical and optical properties
(2010-05)The objective of this study is to investigate the effects anti-biofouling additives have on the optical and mechanical properties in several transparent polymer systems. The resulting effects on mechanical and optical ... -
Partial nucleotide sequence, mapping and relative expression of a xiphophorus fish NF1 gene
(2001-05)No abstract prepared. -
Divergence of the RNA Recognition Motif in Vertebrate LARP6 Proteins
(2019-05)The La-related proteins (LARPs) share a conserved RNA-binding unit composed of a La Motif and an RNA Recognition Motif (RRM), which recognizes diverse RNA substrates. LARPs use different surfaces on their RRMs to bind ... -
Hydrosilation polymerization in supercritical carbon dioxide
(2000-12)Supercritical carbon dioxide (ScC02) has a number of unique and beneficial properties that have been utilized in several polymerization reactions. This thesis comprises the novel approach of the formation of polysilanes ...
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Interactions Between DNA Double-strand Break Repair Proteins and the Telomerase DNA Replication Complex
(2006-08)No abstract prepared.
