RSS 1.0Theses and Dissertations-Chemistry and Biochemistry
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DNA Double-Strand Break Repair Deficiency is Associated with Changes in Cell Cycling and Cell Morphology in Saccharomyces Cerevisiae
(2017-04-26)No abstract prepared. -
The Identification of Residues Critical in the Extracellular Domain of the Beta Subunit of Epithelial Sodium Channels
(2017-05)No abstract prepared. -
Identification of Accessory Proteins and Their Impact on the Expression of the Epithelial Sodium Channel (ENaC)
(2017-05)The epithelial sodium channel (ENaC) plays a crucial role in ensuring proper Na+ balance in the body. In the nephron, ENaC regulates the final 3-5% reabsorption of Na+ and is a limiting factor for Na+ reabsorption in the ... -
Stability Studies of Rooperol and Analogues by In Vitro Metabolism With HPLC/MS Detection
(2019-04-29)African Potato, Hypoxis hemerocallidea, has a long history of use by the indigenous people of South Africa to treat cancer and a variety of other diseases. Extracts from the corm contain the norligan bisglycoside hypoxoside, ... -
Synthesis and Characterization of Novel Thiophene-Based Electroactive Polymers
(2019-04-25)Electroactive polymers show great promise in a variety of applications, from chemical sensors to energy storage. Their properties such as solubility and band gap can be tailored through the strategic addition of substituents ... -
Glucuronide Prodrug of a Naturally Derived Cytotoxic Product
(2019-04-26)<p>African Potato (Hypoxis hemerocallidea) is utilized as a medicinal plant in South Africa to treat disorders such as cancer, prostate hyperplasia, and cardiac disease. The corm of H. hemerocallidea contains high levels ... -
Elucidation of Critical Residues Within the Extracellular Loop of the Epithelial Sodium Channel
(2016-12-01)The epithelial sodium channel (ENaC) is a membrane protein complex located in the distal tubule of the nephron in the kidney which is responsible for the reabsorption of the final 3-5% of sodium from the urine back into ... -
Biochemical Analysis of Evolutionary Divergent Vertebrate Larp6 Proteins
(2017-04-27)The La-related proteins (LARPs) contain a conserved bipartite RNA binding domain, called the La module, which consists of the La motif and an RNA recognition motif (RRM). Across the LARP subfamilies, the La module ... -
Recombinant Expression and Purification of LARP6 Proteins from Arabidopsis thaliana
(2017-04-20)No abstract prepared. -
Aptamer-Based Biosensor for Platelet-Derived Growth Factor-bb using Fluorescence Resonance Energy Transfer
(2017-05-02)No abstract prepared. -
Polyaromatic Cores for Enhanced Conductivity in Inherently Conductive Polymers (ICPs)
(2017-07-21)The discovery of Inherently Conductive Polymers (ICPs), also known as “synthetic metals”, is an attracting class of materials as a promising alternative for metallic semiconductors and conductors, which combine the positive ... -
Characterizing the ligand specificity of the RNA binding protein LARP6
(2017-04-25)The La-related proteins are a superfamily of RNA-binding proteins characterized by a unique RNA binding domain that is comprised of two subdomains, the La motif (LAM) and the RNA recognition motif (RRM), which are connected ... -
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Impact of Processing Parameters on Conductive Polymer Electroactivity
(2018-04-20)Soft-templating techniques have been applied to organic soluble polymer systems that produce a large variety of film morphologies. Film morphology is observed to greatly influence the system’s electrochemical current ... -
Determining the Role of ATP6V0E1 of the Vacuolar-ATPase in Regulating Neuroblastoma Cell Survival and Differentiation
(2018-04-24)Neuroblastoma is one of the leading causes of cancer-related childhood deaths. Neuroblastoma arises from the developing sympathetic nervous system where neural crest cells fail to complete the differentiation process. The ... -
Purification, Characterization, and Active Site Studies of 2-(2'-Hydroxyphenyl) Benzenesulfinate Desulfinase (DSZB) from Nocardia Asteroides Sp. Strain A3H1
(2009-12-05)Dibenzophene (DBT) and its complex heterocyclic derivatives comprise most of the sulfur that contaminates fossil fuels. The 2-(2´-hydroxyphenyl) benzenesulfinate desulfinase (DszB) enzyme metabolize sulfur from DBT compounds. ... -
Quantifying the ability of RF-amide neuropeptide analogs to promote amyloidosis of recombinant Human Prion Protein.
(2015-10-26)No abstract prepared. -
