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dc.contributor.authorJackson, Corey S. ( )
dc.contributor.authorBarrett, Douglas W. ( )
dc.contributor.authorShumake, Jason ( Orcid Icon )
dc.contributor.authorGonzales, Elisa ( )
dc.contributor.authorGonzalez-Lima, F. ( )
dc.contributor.authorLane, Michelle A. ( Orcid Icon )
dc.identifier.citationJackson, C., Barrett, D. W., Shumake, J., Gonzales, E., Gonzalez-Lima, F., Lane, M. A. (2018). Maternal omega-3 fatty acid intake during neurodevelopment does not affect pup behavior related to depression, novelty, or learning. BMC Research Notes, 11 : 812.en_US

Objective: Previously, we showed that consumption of a diet supplemented with omega-3 polyunsaturated fatty acids (n-3FAs) for two rounds of gestation and lactation increased the ability of rat dams to cope with stress when compared to dams that ingested a diet lacking n-3FAs. The objective of this study was to determine if the diets of these dams affected the behavior of their pups later in life. To isolate the neurodevelopmental effects of n-3FAs, pups from the second gestation were weaned to a diet adequate in n-3FAs. Pup testing began at 8 weeks of age and consisted of the forced swim, open field, and hole board tests to examine depression-related behavior, reaction to novelty, and learning and memory, respectively.

Results: Given the considerable difference in the n-3FA content of the maternal diet, we expected a large effect size, however with the exception of rearing duration, maternal diet did not affect behavior in any of the tests conducted. These results suggest that maternal n-3FA supplementation during neurodevelopment likely does not affect offspring behavior when a diet adequate in n-3FA is provided post-weaning. Rather, we hypothesize that brain n-3FAs at the time of testing confer altered behavior and corroborate the need for additional research.

dc.format.extent7 pages
dc.format.medium1 file (.pdf)
dc.publisherBioMed Centralen_US
dc.sourceBMC Research Notes, 2018, Vol. 11, Article 812
dc.subjectn-3 fatty acids
dc.subjectNovelty reactivity learning
dc.titleMaternal Omega-3 Fatty Acid Intake During Neurodevelopment Does Not Affect Pup Behavior Related to Depression, Novelty, or Learningen_US
dc.rights.holder© 2018 The Authors.
dc.rights.licenseCreative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
txstate.departmentFamily and Consumer Sciences



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