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dc.contributor.authorJackson, Corey S.
dc.contributor.authorBarrett, Douglas W.
dc.contributor.authorShumake, Jason
dc.contributor.authorGonzales, Elisa
dc.contributor.authorGonzalez-Lima, F.
dc.contributor.authorLane, Michelle A.
dc.date.accessioned2019-08-05T17:32:12Z
dc.date.available2019-08-05T17:32:12Z
dc.date.issued2018
dc.identifier.citationJackson, C., Barrett, D. W., Shumake, J., Gonzales, E., Gonzalez-Lima, F., Lane, M. A. (2018). Maternal omega-3 fatty acid intake during neurodevelopment does not affect pup behavior related to depression, novelty, or learning. BMC Research Notes, 11 : 812.en_US
dc.identifier.issn1756-0500
dc.identifier.urihttps://digital.library.txstate.edu/handle/10877/8455
dc.description.abstractObjective: Previously, we showed that consumption of a diet supplemented with omega-3 polyunsaturated fatty acids (n-3FAs) for two rounds of gestation and lactation increased the ability of rat dams to cope with stress when compared to dams that ingested a diet lacking n-3FAs. The objective of this study was to determine if the diets of these dams affected the behavior of their pups later in life. To isolate the neurodevelopmental effects of n-3FAs, pups from the second gestation were weaned to a diet adequate in n-3FAs. Pup testing began at 8 weeks of age and consisted of the forced swim, open field, and hole board tests to examine depression-related behavior, reaction to novelty, and learning and memory, respectively. Results: Given the considerable difference in the n-3FA content of the maternal diet, we expected a large effect size, however with the exception of rearing duration, maternal diet did not affect behavior in any of the tests conducted. These results suggest that maternal n-3FA supplementation during neurodevelopment likely does not affect offspring behavior when a diet adequate in n-3FA is provided post-weaning. Rather, we hypothesize that brain n-3FAs at the time of testing confer altered behavior and corroborate the need for additional research.en_US
dc.formatText
dc.format.extent7 pages
dc.format.medium1 file (.pdf)
dc.language.isoen_USen_US
dc.publisherBioMed Centralen_US
dc.sourceBMC Research Notes, 2018, Vol. 11, Article 812
dc.subjectn-3 fatty acids
dc.subjectDepression
dc.subjectNovelty reactivity learning
dc.subjectMemory
dc.subjectNeurodevelopment
dc.titleMaternal Omega-3 Fatty Acid Intake During Neurodevelopment Does Not Affect Pup Behavior Related to Depression, Novelty, or Learningen_US
txstate.documenttypeArticle
dc.identifier.doihttps://doi.org/10.1186/s13104-018-3915-3
dc.rights.licenseThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
txstate.departmentFamily and Consumer Sciences


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