Aptamer Functionalized Electroactive Polymers for Detection of Biomolecules

dc.contributor.advisorIrvin, Jennifer
dc.contributor.advisorBetancourt, Tania
dc.contributor.authorBurke, Kelli
dc.contributor.committeeMemberBooth, Chad
dc.date.accessioned2022-01-24T18:15:39Z
dc.date.available2022-01-24T18:15:39Z
dc.date.issued2020-12
dc.description.abstract3,4-Propylenedioxythiophene (ProDOT) based monomers were synthesized and polymerized via electrochemical polymerization. The electrochemical properties of the resulting polymer films were studied in organic and aqueous solutions using cyclic voltammetry (CV). The polymer films were then functionalized with an adenosine-specific aptamer via click chemistry. Aptamer functionalization was confirmed by fluorescence microscope imaging and by CV. Aptamer functionalized polymer films were used to electrochemically detect adenosine at different concentrations to evaluate the analytical sensing ability of the fabricated biosensor.
dc.description.departmentChemistry and Biochemistry
dc.formatText
dc.format.extent159 pages
dc.format.medium1 file (.pdf)
dc.identifier.citationBurke, K. K. (2020). <i>Aptamer functionalized electroactive polymers for detection of biomolecules</i> (Unpublished thesis). Texas State University, San Marcos, Texas.
dc.identifier.urihttps://hdl.handle.net/10877/15200
dc.language.isoen
dc.subjectElectroactive
dc.subjectPolymer
dc.subjectAptamer
dc.subjectElectrochemistry
dc.subjectBiosensor
dc.titleAptamer Functionalized Electroactive Polymers for Detection of Biomolecules
dc.typeThesis
thesis.degree.departmentChemistry and Biochemistry
thesis.degree.disciplineChemistry
thesis.degree.grantorTexas State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science

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