Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Simple item page
dc.contributor.authorCantu, Travis
dc.contributor.authorRodier, Bradley
dc.contributor.authorIszard, Zachary
dc.contributor.authorKilian, Alissa
dc.contributor.authorPattani, Varun P.
dc.contributor.authorWalsh, Kyle
dc.contributor.authorWeber, Katharina
dc.contributor.authorTunnell, James
dc.contributor.authorBetancourt, Tania
dc.contributor.authorIrvin, Jennifer A.
dc.date.accessioned2020-05-26T16:59:14Z
dc.date.available2020-05-26T16:59:14Z
dc.date.issued2016-01
dc.description.abstractA method for the synthesis of electroactive polymers is demonstrated, starting with the synthesis of extended conjugation monomers using a three-step process that finishes with Negishi coupling. Negishi coupling is a cross-coupling process in which a chemical precursor is first lithiated, followed by transmetallation with ZnCl2. The resultant organozinc compound can be coupled to a dibrominated aromatic precursor to give the conjugated monomer. Polymer films can be prepared via electropolymerization of the monomer and characterized using cyclic voltammetry and ultraviolet-visible-near infrared (UV-Vis-NIR) spectroscopy. Nanoparticles (NPs) are prepared via emulsion polymerization of the monomer using a two-surfactant system to yield an aqueous dispersion of the polymer NPs. The NPs are characterized using dynamic light scattering, electron microscopy, and UV-Vis-NIR-spectroscopy. Cytocompatibility of NPs is investigated using the cell viability assay. Finally, the NP suspensions are irradiated with a NIR laser to determine their effectiveness as potential materials for photothermal therapy (PTT).
dc.description.departmentChemistry and Biochemistry
dc.description.departmentMaterials Science, Engineering, and Commercialization
dc.formatText
dc.format.extent13 pages
dc.format.medium1 file (.pdf)
dc.identifier.citationCantu, T., Rodier, B., Iszard, Z., Kilian, A., Pattani, V., Walsh, K., Weber, K., Tunnell, J., Betancourt, T., & Irvin, J. (2016). Electroactive polymer nanoparticles exhibiting photothermal properties. Journal of Visualized Experiments(107), e53631.
dc.identifier.doihttps://doi.org/10.3791/53631
dc.identifier.urihttps://hdl.handle.net/10877/10313
dc.language.isoen
dc.publisherJournal of Visualized Experiments
dc.rights.holder© 2016 Journal of Visualized Experiments.
dc.sourceJournal of Visualized Experiments, 2016, No. 107, Article e53631.
dc.subjectengineering
dc.subjectelectroactive polymers
dc.subjectconductive polymers
dc.subjectnegishi coupling
dc.subjectelectrochemistry
dc.subjectnanoparticles
dc.subjectemulsion polymerization
dc.subjectphotothermal therapy
dc.subjectChemistry and Biochemistry
dc.titleElectroactive Polymer Nanoparticles Exhibiting Photothermal Properties
dc.typeArticle

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
jove-protocol-53631-electroactive-polymer-nanoparticles-exhibiting-photothermal-properties.pdf
Size:
801.1 KB
Format:
Adobe Portable Document Format
Description:
Download

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.54 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

College of Science and Engineering