Modulation of Vitamin D Status by Gut Microbiota: Impact on Depression and Anxiety-related Behavior in Adult C57BL/6J Mice

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dc.contributor.authorKoh, Gar Yee
dc.contributor.authorRenteria, Karisa
dc.contributor.authorConstantine, Ethan
dc.contributor.authorTeoh, Chin May
dc.contributor.authorCooper, Analynn
dc.date.accessioned2023-05-10T13:48:10Z
dc.date.available2023-05-10T13:48:10Z
dc.date.issued2023-04
dc.description.abstractDepression and anxiety disorders are among the most common mental health disorders that affect U.S. adults today (1). As a result of the COVID-19 pandemic, symptoms of both disorders were exacerbated globally (2). In addition to the classic role of vitamin D (VD) in bone health, suboptimal levels of VD has shown to increase risk for inflammation, immune function, and cognitive function. Individuals diagnosed with seasonal affective disorder, a type of depression, frequently have suboptimal levels of VD due to limited sun exposure related to seasonal changes and/or low dietary intake. Vitamin D plays a vital role in physiological functions like mitigating inflammatory status and restores calcium and neurotransmitter imbalance (3). Along with VD, growing evidence suggests gut microbiota likely play a role in neuropsychiatric disorders (4, 5) as supplementation with pre- and probiotic has shown to alleviate mental health disorders (6). To date, the mechanisms by which VD alleviate depression and anxiety-related symptoms and whether the protective effect is dependent on gut microbiota remains unclear.
dc.description.departmentFamily and Consumer Sciences
dc.description.departmentBiology
dc.formatImage
dc.format.extent1 page
dc.format.medium1 file (.pdf)
dc.identifier.citationKoh, G. Y., Renteria, K. M., Constantine, E., Teoh, C. M., & Cooper, A. (2023). Modulation of vitamin D status by gut microbiota: Impact on depression and anxiety-related behavior in adult C57BL/6J mice. Poster presented at the Health Scholar Showcase, Translational Health Research Center, San Marcos, Texas.
dc.identifier.urihttps://hdl.handle.net/10877/16746
dc.language.isoen
dc.sourceHealth Scholar Showcase, 2023, Texas State University Translational Health Science Center, San Marcos, Texas, United States.
dc.subjectdepression
dc.subjectanxiety
dc.subjectgut microbiota
dc.subjectvitamin D
dc.titleModulation of Vitamin D Status by Gut Microbiota: Impact on Depression and Anxiety-related Behavior in Adult C57BL/6J Mice
dc.typePoster

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